Multiscale Microscopy of Biomaterials & Biointerfaces

Welcome to the Grandfield Research Group at McMaster University, Canada. Our team focuses on the development and characterization of biomaterials– pioneering the investigation of bone-implant interfaces and mineralized tissues with multiscale, multidimensional and correlative microscopies. The insights made through this work are contributing to the design of novel materials for improved implant success, and an improved understanding of healthy and pathological mineralized tissues, such as bones and teeth.





Welcoming incoming PhDs Jeromy, Alyssa and undergrads Kamal, Ryan

Summer research continues! Welcome Ariana, Andrew and Yushi

Select Recent Publications

Wang, X., Yang, J., Andrei, C.M., Soleymani, L., Grandfield, K. (2018) Biomineralization of calcium phosphate revealed by in situ liquid-phase electron microscopy. Communications Chemistry, 1 (80): 10.1038/s42004-018-008.

Binkley, D.M., Deering, J., Yuan, H., Gourrier, A., Grandfield, K.(2020) Ellipsoidal mesoscale mineralization pattern in human cortical bone revealed in 3D by plasma focused ion beam serial sectioning. Journal of Structural Biology, 212(2): 107615.

Lee, B.E.J., Shahin-Shamsabadi, A., Wong, M., Raha, S., Selvaganapathy, P.R. Grandfield, K. (2019) A Bioprinted in vitro Model for Osteoblast to Osteocyte Transformation by Changing Mechanical Properties of the ECM. Advanced Biosystems. Online August 21, 2019.

Current Events

Grandfield Research Group | Dr. Kathryn Grandfield | Associate Professor | Materials Science and Engineering School of Biomedical Engineering | McMaster University,  ABB C305 | 1280 Main St W, Hamilton ON Canada L8S 4L7

Research funded by:

Multiscale Microscopy of Biomaterials & Biointerfaces