Welcome to the Grandfield Research Group at McMaster University, Canada. Our team focuses on the development and characterization of biomaterials– pioneering the investigation of bone-implant interfaces and mineralized tissues with multiscale, multidimensional and correlative microscopies. The insights made through this work are contributing to the design of novel materials for improved implant success, and an improved understanding of healthy and pathological mineralized tissues, such as bones and teeth.

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In situ biomineralization of CaP published in Nature Communications Chemistry

Kathryn and L. Soleymani win $100k for their Big Idea pitch to Faculty of Engineering

NSERC winner Joe Deering starts his PhD. Welcome!

Recent Publications

Wang, X., Yang, J., Andrei, C.M., Soleymani, L., Grandfield, K. (2018) Biomineralization of calcium phosphate revealed by in situ liquid-phase electron microscopy. Communications Chemistry, 1 (80):

Grandfield, K., Vuong, V., Schwarcz, H.P. (2018) Ultrastructure of Bone: Hierarchical Features from Nanometer to Micrometer Scale Revealed in Focused Ion Beam Sections in the TEM. Calcified Tissue International, 103(6): 606-616.

Wang, X. Y., Langelier, B., Shah, F.A.,  Korinek, A., Bugnet, M., Hitchcock, A.P., Palmquist, A., Grandfield, K. (2018) Biomineralization at Titanium Revealed by Correlative 4D Tomographic and Spectroscopic Methods. Advanced Materials Interfaces, 1800262.

Multiscale Microscopy of Biomaterials

Grandfield Research Group | Dr. Kathryn Grandfield | Assistant Professor | Materials Science and Engineering School of Biomedical Engineering | McMaster University, ETB rm 403 | 1280 Main St W, Hamilton ON Canada L8S 4L7

Research funded by:

Multiscale Microscopy of Biomaterials

Recipient of Petro-Canada Young Innovator Award (2017) and

Ministry of Research, Innovation and Science Early Researcher Award (2018)